Secnidazole

Mechanism of Action
 - Interferes with electron transport in metabolic  

   pathways

- belongs to the category of antiprotozoal agents  

  drugs

-structurally related to 5-nitroimidazoles metronidazole and   tinidazole.

Used in the Treatment of :-

• Intestinal ameobiasis
• Fiardiasis
• Trichomoniasis
• Bacterial vaginosis

Present in pharmacy as :-

   ● Fladazole 500 t  & sachet

   ● Flagentyl 500 t

● Secnidazole 500 t     

   ● Amebazole 1gm t   

   ● Cibazole 1gm t 

   ● Obendazole 1gm t                                                                     

Dosage of Secnidazole :-

For amoebiasis & giardiasis:

►Acute :- 1 day treatment ( Adults 2 gms, Children 30mg/kg body weight) as single dose. 
►Chronic :- 3 days treatment ( Adults 2 gms, Children 30mg/kg body weight) daily

Contra-Indications:-

● Pregnancy

● Lactation

● Hypersensitivity

Side Effects :-

-   Loss of appetite &

• Nausea
• Stomach Discomfort
• Diarrhoea
• Skin Rash
• Fatigue
• Headache